The couple has been an item for four years, and was only recently rumored to be planning to marry and start a family together.
But the National Enquirer claims Jackson and Dupri began battling over the failure of her recent tour, which he managed, and which ended with a string of cancelled concerts because of illness and reports of poor ticket sales.
And sources tell the tabloid the 36-year-old has moved out of the superstar's Los Angeles home, and they have agreed to spend time apart.
The insider says, "Janet and Jermaine finally hit a wall. They were fighting over his management of her career. In the end, she decided to make a break."
Source: NBC Action News